Last update
3/25/2026
Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
L-Lysine (from 637 mg L-Lysine Hydrochloride)
500 mg
**
Top Medical Research Studies
9
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.
After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
Read More
8
We delved into the potential of plant-derived cyclotides, particularly focusing on a modified version of kalata B1, known as [T20K], for autoimmune disorders such as multiple sclerosis. Our investigations revealed that daily doses in mice led to reduced cytokine levels and minimal inflammation, suggesting a promising alternative to traditional immunosuppressive drugs. While the results are encouraging, further research is needed to fully assess the effectiveness of cyclotides in human applications. Overall, cyclotides appear to hold significant promise in the realm of immune modulation.
Read More
Most Useful Reviews
9
Happy customer
1 people found this helpful
I ordered this for my sister - she is thrilled with the results and reported no side effects.
Read More
7.5
Improved joint health
192 people found this helpful
Working well! I've taken Lysine courses multiple times, for a month each time, and intend to do so again. It has really helped with my joints and even gave me a boost in mood and positivity.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.
After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
Read More
8
We delved into the potential of plant-derived cyclotides, particularly focusing on a modified version of kalata B1, known as [T20K], for autoimmune disorders such as multiple sclerosis. Our investigations revealed that daily doses in mice led to reduced cytokine levels and minimal inflammation, suggesting a promising alternative to traditional immunosuppressive drugs. While the results are encouraging, further research is needed to fully assess the effectiveness of cyclotides in human applications. Overall, cyclotides appear to hold significant promise in the realm of immune modulation.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Happy customer
1 people found this helpful
I ordered this for my sister - she is thrilled with the results and reported no side effects.
Read More
7.5
Improved joint health
192 people found this helpful
Working well! I've taken Lysine courses multiple times, for a month each time, and intend to do so again. It has really helped with my joints and even gave me a boost in mood and positivity.
Read More
Frequently Asked Questions
8
We delved into the potential of plant-derived cyclotides, particularly focusing on a modified version of kalata B1, known as [T20K], for autoimmune disorders such as multiple sclerosis. Our investigations revealed that daily doses in mice led to reduced cytokine levels and minimal inflammation, suggesting a promising alternative to traditional immunosuppressive drugs. While the results are encouraging, further research is needed to fully assess the effectiveness of cyclotides in human applications. Overall, cyclotides appear to hold significant promise in the realm of immune modulation.
9
We investigated how RCI001 can help mice with primary Sjögren syndrome. Eight 12-week-old NOD.B10-H2b mice were divided into two groups, one receiving RCI001 and the other a control treatment.
After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
After one week, we noted significant improvements in eye health and tear secretion for the RCI group. They also showed reduced levels of inflammatory markers compared to those treated with the control. Overall, RCI001 proved to effectively reduce inflammation and oxidative stress, suggesting a promising therapeutic option for this autoimmune disease.
References
- Mishra R, Agarwal P, Sharma A, Mittal M, Gulati P, et al. Plant-derived Cyclotides in Immunomodulation and their Therapeutic Potential. Protein Pept Lett. 2025. 10.2174/0109298665364479250214101422
- Kang H, Jung YH, Moon J, Ryu JS, Yoon CH, et al. Efficacy of RCI001 as a Therapeutic Candidate in a Primary Sjögren Syndrome Mouse Model. Cornea. 2025;44:226. 10.1097/ICO.0000000000003696
Data last updated:
